It comes from the Hawthorns, as the hosts’ manager Tony Pulis faces his former club.
Palace won the reverse fixture 2-0 thanks to second-half goals by Yannick Bolasie and Yohan Cabaye.
However, the Eagles have struggled for form in recent weeks, while the Baggies will be buoyed by their win away to Everton in their most recent league fixture.
There have been four penalties in the last four meetings between the sides.
Coverage starts at 5.00pm on Sky Sports 1 and Sky Sports 1 HD. Kick-off 5.30pm
BT Sport will also air live Premier League football today as West Ham United host Sunderland from 12.45pm on BT Sport 1.
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