Five games will take place on Tuesday evening, including Aston Villa v Everton; Leicester City v West Bromwich Albion; Norwich City v Chelsea; Sunderland v Crystal Palace and Bournemouth v Southampton, which will be shown live on BT Sport.
The Saints have won each of the past five league encounters against Bournemouth, including a 2-0 victory at St Mary’s in November’s reverse fixture.
All four of Bournemouth’s wins in their 17 previous league meetings have been at home. Their last league victory over Saints was in 1958 in the old Third Division.
Five more games will be staged on Wednesday night with Liverpool’s clash against Manchester City being broadcast live on BT Sport. Arsenal host Swansea City; Stoke City take on Newcastle United; Tottenham travel to West Ham United and Manchester United entertain Watford in the other four fixtures.
A special midweek edition of Match of the Day will have highlights of all ten games from 10.45pm, Wednesday night on BBC One and BBC One HD.